Muhammadiyah refined the Islamic education curriculum by incorporating Islamic religious education into public schools and secular knowledge to religious schools. In the field of education, Muhammadiyah undertook the modernization of Islamic education, which is essential for the development of Islamic education in Indonesia. The reforms carried out by Muhammadiyah include multidimensional, such as in education, health, economy and culture. Muhammadiyah is an Islamic reform organization that has had a major impact on the progress of Muslims in Indonesia. Sources of educational learning Islamic religion-based multicultural sources of Islamic values as a cornerstone of Islamic education The Foundation consists of the Qur'an and Sunnah Prophet Muhammad SAW that was developed with Ijtihad, Al Maslahah al murincorrectly, Istihsan, Qiyas and so on and from the source of learning it in the Islamic Religious education based multicultural developed with regard to the values of Islam Rahmatan li Al-"alamin that put forward the principles of Islamic Humanist, tolerant, democratic, and accommodating local cultures. Media can also be called tools while commonly used at this time is an audio visual aids, which means audiovisual aids are materials or tools used in the situation to help the writings and words spoken in the transmission of knowledge, attitudes, and ideas in the development of Islamic education be bases multicultural. Learning Media of Islamic religious education. Learning activities are designed to provide a learning experience involving mental and physical processes through interaction between learners, learners with teachers, the environment, and other learning resources in order to achieve basic competencies. In developing a multicultural learning model that must be blessed is a truly multicultural-laden learning activity. Multicultural-based Islamic religious education learning Model. The research method in this article is an observative research on educational institutions in Indonesia from the policy side of government and related educational institutions. Effect of integrated learning model to the students competence including large categories.Abstract: the discussion in this article refers to the development of a multicultural-based Islamic religious education curriculum as an effort to develop the values of religious moderation in Indonesia that have been implemented. Thus, student competence is significantly influenced by the implementation of integrated learning model. (3) There is interaction of learning model and motivation that effect to the student competence. (2) There is a significant difference in the competence of students who high motivation and low motivation in the integrated learning. The result of the research shows that the integrated learning model impact to improvement the students' competence, in the terms of: (1) There is a significant difference in the competence of students who use integrated learning and students who use conventional learning model. Data were collected using observation sheets, tests, and motivation questionnaires. The subjects of the research were eight grades in Junior High School students. This research used quasi experiment method with pre-test post-test group control design. Therefore, the integrated learning is implemented in natural science subject. The students are required to be active in learning and teacher is implemented the various learning methods. Natural science learning is not yet integrated. The students' competency of Junior High School in mastering the natural science concept is still low.